APTO-253 [CAS 916151-99-0]
Partner: MedChemexpress LLC
| CAS No: | 916151-99-0 |
| Applications: | Cancer-Kinase/protease |
| MW: | 367.38 |
| Formula: | C22H14FN5 |
| SMILES: | CC(N1)=C(C(N2)=NC3=C2C4=CC=CN=C4C5=NC=CC=C53)C6=C1C=CC(F)=C6 |
| Purity: | 98.81 |
| Description: | APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Kr�ppel-like factor 4 (KLF4) tumor suppressor[1][2]. APTO-253 has antiarthritic activity[3]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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