Data Sheet

MSDS

Forodesine [CAS 209799-67-7]

CAS No:	209799-67-7
Applications:	Cancer-programmed cell death
MW:	266.25
Formula:	C₁₁H₁₄N₄O₄
SMILES:	O=C1C(NC=C2[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)=C2NC=N1
Purity:	99.88
Description:	Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only