Data Sheet

MSDS

Forodesine (hydrochloride) [CAS 284490-13-7]

CAS No:	284490-13-7
Applications:	Cancer-programmed cell death
MW:	302.7142
Formula:	C₁₁H₁₅ClN₄O₄
SMILES:	O=C1C(NC=C2[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)=C2NC=N1.Cl
Purity:	99.86
Description:	Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only