BAY-747 [CAS 1609342-18-8]
Partner: MedChemexpress LLC
| CAS No: | 1609342-18-8 |
| Applications: | Neuroscience-Neuromodulation |
| MW: | 416.46 |
| Formula: | C22H26F2N4O2 |
| SMILES: | FC(C=CC=C1F)=C1COC2=CC(C)=CN3C2=NC(C)=C3C(NC[C@@](C)(N)CC)=O |
| Description: | BAY-747 (BAY 1165747) is an orally active and brain-penetrant stimulator of soluble guanylate cyclase (sGC). BAY-747 reverses L-NAME induced memory impairments and enhances cognition of rats in the object location task (OLT). BAY-747 also decreases blood pressure in both conscious normotensive and spontaneously hypertensive rats (SHR). BAY-747 improves function of the skeletal muscle associated with Duchenne muscular dystrophy (DMD) in mdx/mTRG2 mice model[1][2][3]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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