(Aminooxy)acetamide-Val-Cit-PAB-MMAE [CAS 2446645-88-9]
Partner: MedChemexpress LLC
| CAS No: | 2446645-88-9 |
| MW: | 1196.48 |
| Formula: | C60H97N11O14 |
| SMILES: | C[C@@H](C(N[C@H](C)[C@H](C1=CC=CC=C1)O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CON)=O)=O)=O)=O)=O)=O)=O)OC |
| Purity: | 97.01 |
| Description: | (Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) is an intermediate used in the synthetic preparation of drug-linker conjugates for ADC. (Aminooxy)acetamide-Val-Cit-PAB-MMAE is conjugated to polyamide via oxime bond formation to form MMAE polyamide conjugate. Then MMAE polyamide conjugate can be conjugated to Trastuzumab, to make ADC[1]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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