(�)-AMG 487 [CAS 947536-03-0]
Partner: MedChemexpress LLC
CAS No: | 947536-03-0 |
Applications: | Cancer-programmed cell death |
MW: | 603.59 |
Formula: | C32H28F3N5O4 |
SMILES: | O=C(N(C(C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5 |
Description: | (�)-AMG 487 is a racemate of AMG 487. AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively[1]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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