Data Sheet

MSDS

ARN1468 [CAS 1381459-14-8]

CAS No:	1381459-14-8
Applications:	COVID-19-immunoregulation
MW:	354.33
Formula:	C₁₆H₁₇F₃N₄O₂
SMILES:	O=C(C1=C(N(C2=CC=C(OC(F)(F)F)C=C2)N=C1)N)C3CCNCC3
Purity:	99.34
Description:	ARN1468 (compound 5) is an orally active and potent serpins inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 ?M[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only