STAT3-IN-11 [CAS 2503096-50-0]
Partner: MedChemexpress LLC
| CAS No: | 2503096-50-0 |
| Applications: | Cancer-Kinase/protease |
| MW: | 335.35 |
| Formula: | C20H17NO4 |
| SMILES: | O=C(NCCC(C1=O)=C(C)C(C2=C1C(O)=CC=C2)=O)C3=CC=CC=C3 |
| Purity: | 98.30 |
| Description: | STAT3-IN-11 (7a) is a selective STAT3 inhibitor that inhibits the phosphorylation of STAT3 at site pTyr705. STAT3-IN-11 inhibits the phosphorylation of downstream genes (Survivin and Mcl-1) without affecting its upstream tyrosine kinases (Src and JAK2) levels and p-STAT1 expression. STAT3-IN-11 can induce cancer cell apoptosis, which is potential for the discovery of effective STAT3 inhibitors and antitumor agents against cancers[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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