XL01126
Partner: MedChemexpress LLC
| Applications: | Neuroscience-Neurodegeneration |
| MW: | 1019.69 |
| Formula: | C50H64ClFN10O6S2 |
| SMILES: | O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(SC[C@@H]3CC[C@@H](CN4CCN(C(C5=CC=C(NC6=NC=C(Cl)C(NC)=N6)C(OC)=C5)=O)CC4)CC3)C)=O)C[C@H](O)C1)NCC7=CC=C(C8=C(C)N=CS8)C=C7 |
| Purity: | 99.81 |
| Description: | XL01126 is a potent degrader of LRRK2 with DC50s of 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2), respectively. XL01126 can cross blood-brain barrier and be used as a degrader probe in Parkinson�s disease research. XL01126 exerts function of study of non-catalytic and scaffolding functions of LRRK2[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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