MNK8 [CAS 2055078-49-2]
Partner: MedChemexpress LLC
CAS No: | 2055078-49-2 |
Applications: | Cancer-Kinase/protease |
MW: | 252.27 |
Formula: | C15H12N2O2 |
SMILES: | O=C1N(C)C(C=C(C2=C3C=CC=CC3=CC=C2)N1)=O |
Purity: | 99.76 |
Description: | MNK8 is a potent STAT3 (signal transducer and activator of transcription 3) inhibitor. MNK8 inhibits STAT3 activation and reduced its DNA binding ability. MNK8 shows good growth inhibition against hepatocellular carcinoma (HCC) cells. MNK8 induces apoptosis in HCC cells. MNK8 reduces prosurvival proteins expression and migration/invasion of HCC cells[1]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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