PARP-1-IN-2 [CAS 684234-55-7]
Partner: MedChemexpress LLC
| CAS No: | 684234-55-7 |
| Applications: | Cancer-programmed cell death |
| MW: | 424.28 |
| Formula: | C22H15Cl2N3O2 |
| SMILES: | O=C(NC1=CC=CC(Cl)=C1)CN(N=C(C2=CC=C(Cl)C=C2)C3=C4C=CC=C3)C4=O |
| Purity: | 98.80 |
| Description: | PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 149 nM. PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. PARP1-IN-2 can induce A549 cells apoptosis[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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