Data Sheet

MSDS

Amsilarotene [CAS 125973-56-0] (10mM in DMSO)

CAS No:	125973-56-0
Applications:	Cancer-Kinase/protease
MW:	385.60
Formula:	C₂₀H₂₇NO₃Si₂
SMILES:	C[Si](C)(C)C1=CC(C(NC2=CC=C(C(O)=O)C=C2)=O)=CC([Si](C)(C)C)=C1
Purity:	99.70
Description:	Amsilarotene (TAC-101; Am 555S), an orally active synthetic retinoid, has selective affinity for retinoic acid receptor ? (RAR-?) binding with Ki of 2.4, 400 nM for RAR-? and RAR-?. Amsilarotene induces the apoptotic of human gastric cancer, hepatocellular carcinoma and ovarian carcinoma cells. Amsilarotene can be used for the research of cancer[1][2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only