ADAMTS-5-IN-3 [CAS 2688733-96-0]
Partner: MedChemexpress LLC
CAS No: | 2688733-96-0 |
Applications: | Metabolism-protein/nucleotide metabolism |
MW: | 424.32 |
Formula: | C20H23Cl2N3O3 |
SMILES: | O=C(N1C[C@@H](C2=CC(Cl)=C(Cl)C=C2CC1)C)CC[C@]3(C4CC4)C(NC(N3)=O)=O |
Purity: | 98.90 |
Description: | ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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