(4S)-PROTAC SOS1 degrader-1 (diTFA)
Partner: MedChemexpress LLC
MW: | 1279.84 |
Formula: | C61H78ClF7N10O8S |
SMILES: | O=C(N[C@@H](C(C)(C)C)C(N1C[C@@H](O)C[C@H]1C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)CCCCCCCCN4CCN(CC4)C5=C6N=C(N7CC8(CNC8)C7)N(CC9=CC(C)=C(F)C(C)=C9)C6=CC(Cl)=C5.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F |
Purity: | 98.09 |
Description: | (4S)-PROTAC SOS1 degrader-1 (diTFA) is a potent PROTAC SOS1 degrader. (4S)-PROTAC SOS1 degrader-1 (diTFA) decreases the expression of pERK and RAS-GTP level in a dose-dependent manner. (4S)-PROTAC SOS1 degrader-1 (diTFA) significantly inhibits the tumor growth in vivo[1]. |
Shipping Conditions: | Ship on cold packs |
Usage: | Research Use Only |
Insight Biotechnology Ltd reserves the right to change pricing without notice