Data Sheet

MSDS

SB 271046 (Hydrochloride) [CAS 209481-24-3]

CAS No:	209481-24-3
Applications:	Neuroscience-Neuromodulation
MW:	488.45
Formula:	C₂₀H₂₃Cl₂N₃O₃S₂
SMILES:	ClC1=CC2=C(C=C1)SC(S(=O)(NC3=CC=C(C(N4CCNCC4)=C3)OC)=O)=C2C.[H]Cl
Purity:	99.63
Description:	SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 ?M)[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only