MPO-IN-1 [CAS 2471981-21-0]
Partner: MedChemexpress LLC
CAS No: | 2471981-21-0 |
Applications: | COVID-19-immunoregulation |
MW: | 400.90 |
Formula: | C24H21ClN4 |
SMILES: | ClC1=C(C(C2=CC3=C(C=CN3)C=C2)=CN4C5=CC=C(CN(C)C)C=C5)C4=NC=C1 |
Purity: | 99.02 |
Description: | MPO-IN-1 is a potent, orally active, and irreversible indole-containing inhibitor of myeloperoxidase (MPO). MPO-IN-1 has IC50s of 2.6 ?M and 5.3 ?M for MPO and thyroid peroxidase (TPO), respectively. MPO-IN-1 inhibits MPO activity in an acute mouse model of inflammation[1]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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