(+)-JNJ-A07 [CAS 2135640-93-4]
Partner: MedChemexpress LLC
CAS No: | 2135640-93-4 |
Applications: | COVID-19-anti-virus |
MW: | 578.96 |
Formula: | C28H26ClF3N2O6 |
SMILES: | OC(CCCOC1=CC(OC)=CC(NC(C2=CC=C(C=C2)Cl)C(N3C4=CC(OC(F)(F)F)=CC=C4CC3)=O)=C1)=O.[Rotation (+)] |
Purity: | 98.0 |
Description: | (+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models[1]. |
Shipping Conditions: | Ship on cold packs |
Usage: | Research Use Only |
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