Data Sheet

MSDS

MGH-CP1 [CAS 896657-58-2]

CAS No:	896657-58-2
Applications:	Cancer-programmed cell death
MW:	368.50
Formula:	C₂₀H₂₄N₄OS
SMILES:	O=C(CSC1=NN=CN1)NC2=CC=C(C=C2)C3(C[C@H](C4)C5)C[C@H]5C[C@H]4C3
Purity:	99.21
Description:	MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only