NMDAR/TRPM4-IN-2 (free base) [CAS 1353979-43-7]
Partner: MedChemexpress LLC
| CAS No: | 1353979-43-7 |
| Applications: | Neuroscience-Neurodegeneration |
| MW: | 257.17 |
| Formula: | C11H17BrN2 |
| SMILES: | NCCN(CC1=CC=CC(Br)=C1)CC |
| Purity: | 99.24 |
| Description: | NMDAR/TRPM4-IN-2 free base (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 free base shows neuroprotective activity. NMDAR/TRPM4-IN-2 free base prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 ?M. NMDAR/TRPM4-IN-2 free base protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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