Data Sheet

MSDS

R1530 [CAS 882531-87-5]

CAS No:	882531-87-5
Applications:	Cancer-Kinase/protease
MW:	356.78
Formula:	C₁₈H₁₄ClFN₄O
SMILES:	CC(NN1)=C2C1=NC3=CC(OC)=C(F)C=C3C(C4=CC=CC=C4Cl)=N2
Purity:	99.06
Description:	R1530 is a highly potent, orally active, dual-acting mitosis/angiogenesis inhibitor, with anti-tumor and anti-angiogenic activities. R1530 is a multikinase inhibitor which binds to 31 kinases with Kd values of <500 nM. R1530 inhibits VGFR2 and FGFR1 with IC50 of 10 nM and 28 nM, respectively. R1530 triggers apoptosis (mitotic catastrophe) or senescence[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only