Data Sheet

MSDS

MG-132 [CAS 133407-82-6]

CAS No:	133407-82-6
Applications:	Cancer-Kinase/protease
MW:	475.62
Formula:	C₂₆H₄₁N₃O₅
SMILES:	O=C(OCC1=CC=CC=C1)N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C([H])=O)CC(C)C)=O)=O)CC(C)C
Purity:	99.97
Description:	MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 ?M, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis[1][2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only