Data Sheet

MSDS

Lumasiran [CAS 1834610-13-7]

CAS No:	1834610-13-7
Applications:	Metabolism-protein/nucleotide metabolism
MW:	16339.00 (AS: 7631.0 +SS: 8708.0)
Formula:	C₅₃₀H₇₁₂F₁₀N₁₇₃O₃₂₀P₄₃S₆
SMILES:	[Lumasiran]
Purity:	95.37
Description:	Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1)[1][2].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only