NVP-TAE 226 [CAS 761437-28-9] (10mM in DMSO)
Partner: MedChemexpress LLC
| CAS No: | 761437-28-9 |
| Applications: | Cancer-Kinase/protease |
| MW: | 468.94 |
| Formula: | C23H25ClN6O3 |
| SMILES: | O=C(C1=C(C=CC=C1)NC2=NC(NC3=C(C=C(C=C3)N4CCOCC4)OC)=NC=C2Cl)NC |
| Purity: | 99.92 |
| Description: | NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively[1][2]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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