Data Sheet

MSDS

HS-27 [CAS 1562024-11-6]

CAS No:	1562024-11-6
Applications:	Cancer-programmed cell death
MW:	993.13
Formula:	C₅₂H₆₀N₆O₁₂S
SMILES:	O=C(N)C1=CC=C(N2N=C(C)C3=C2CC(C)(C)CC3=O)C=C1NCCCOCCOCCOCCOCCOCCCNC(NC4=CC5=C(C6(C7=C(OC8=C6C=CC(O)=C8)C=C(O)C=C7)OC5=O)C=C4)=S
Purity:	98.48
Description:	HS-27, a fluorescently-tethered Hsp90 inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see-and-treat paradigm in breast cancer[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only