LC3-mHTT-IN-AN2 [CAS 7758-73-8] (10mM in DMSO)
Partner: MedChemexpress LLC
CAS No: | 7758-73-8 |
Applications: | Neuroscience-Neurodegeneration |
MW: | 254.24 |
Formula: | C15H10O4 |
SMILES: | OC1=C2C(OC(C=C2C3=CC=CC=C3)=O)=CC(O)=C1 |
Purity: | 96.07 |
Description: | LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1]. |
Shipping Conditions: | Ship on cold packs |
Usage: | Research Use Only |
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