LC3-mHTT-IN-AN1 [CAS 486443-73-6]
Partner: MedChemexpress LLC
| CAS No: | 486443-73-6 |
| Applications: | Neuroscience-Neurodegeneration |
| MW: | 411.04 |
| Formula: | C15H9Br2NO3 |
| SMILES: | BrC1=CC=C(C/2=C1)NC(C2=C/C3=CC(Br)=C(C(O)=C3)O)=O |
| Purity: | 98.99 |
| Description: | LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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