Data Sheet

MSDS

VP3.15 (dihydrobromide) [CAS 1281681-33-1]

CAS No:	1281681-33-1
Applications:	Neuroscience-Neuromodulation
MW:	528.30
Formula:	C₂₀H₂₄Br₂N₄OS
SMILES:	[H]Br.[H]Br.N1(CC/N=C2N=C(C3=CC=CC=C3)N(C4=CC=CC=C4)S/2)CCOCC1
Purity:	98.01
Description:	VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 ?M and 0.88 ?M for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS)[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only