Description: | Mps1-IN-7 is a potent MPS1 inhibitor (IC50 of 0.020 ?M) over JNK1 and JNK2 (JNK1 IC50= 0.11 ?M, JNK2 IC50=0.22 ?M). Mps1-IN-7 inhibit SW620, CAL51, Miapaca-2, RMG1 cell growth with GI50 values of 0.065, 0.068, 0.25, and 0.110 ?M,respectively[1]. |