KHK-IN-1 (hydrochloride) [CAS 1303470-48-5]
Partner: MedChemexpress LLC
CAS No: | 1303470-48-5 |
MW: | 459.01 |
Formula: | C21H27ClN8S |
SMILES: | [H]Cl.CSC(C=CC=C1)=C1NC2=NC(N3CCNCC3)=NC4=C2N=CN=C4NCC5CC5 |
Purity: | 98.47 |
Description: | KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity[1]. |
Shipping Conditions: | Ship on cold packs |
Usage: | Research Use Only |
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