Data Sheet

MSDS

Tankyrase-IN-2 [CAS 1588870-36-3]

CAS No:	1588870-36-3
Applications:	Cancer-programmed cell death
MW:	316.30
Formula:	C₁₇H₁₄F₂N₂O₂
SMILES:	O=C1NC(C2=CC=C(C(C)(O)C)C=C2)=NC3=C1C=C(F)C=C3F
Purity:	99.60
Description:	Tankyrase-IN-2 (compound 5k) is a potent, selective, and orally active tankyrase inhibitor (IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectively). Tankyrase-IN-2 has favorable physicochemical profile and pharmacokinetic properties modulating Wnt pathway activity in a colorectal xenograft model[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only