Data Sheet

MSDS

(R)-OP-1074 [CAS 1443752-77-9]

CAS No:	1443752-77-9
MW:	457.56
Formula:	C₂₉H₃₁NO₄
SMILES:	OC1=CC=C2C(C)=C(C3=CC=C(O)C=C3)[C@@H](C4=CC=C(OCCN5C[C@H](C)CC5)C=C4)OC2=C1
Purity:	98.24
Description:	(R)-OP-1074 is the inactive isomer of OP-1074 (HY-125263), and can be used as an experimental control. OP-1074 is a pure antiestrogen and a selective ER degrader (PA-SERD), shows specific antiestrogenic activity for ER? and ER?, inhibits 17?-estradiol (E2)-stimulated transcriptional activity with IC50 of 1.6 and 3.2?nM, respectively[1].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only