KY-05009 [CAS 1228280-29-2]
Partner: MedChemexpress LLC
| CAS No: | 1228280-29-2 |
| Applications: | Cancer-Kinase/protease |
| MW: | 352.41 |
| Formula: | C18H16N4O2S |
| SMILES: | O=C(C1=C(NC(C2=CC=C(C)C=C2)=O)SC(NC3=CC=CC=C3)=N1)N |
| Purity: | 99.24 |
| Description: | KY-05009 is an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM. KY-05009 pharmacologically inhibits TGF-?1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells. KY-05009 inhibits the protein expression of TNIK and transcriptional activity of Wnt target genes and induces apoptosis in cancer cells. KY-05009 exerts anti-cancer activity[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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