Voruciclib [CAS 1000023-04-0]
Partner: MedChemexpress LLC
| CAS No: | 1000023-04-0 |
| Applications: | Cancer-Kinase/protease |
| MW: | 469.84 |
| Formula: | C22H19ClF3NO5 |
| SMILES: | O=C1C=C(C2=CC=C(C(F)(F)F)C=C2Cl)OC3=C([C@H]4[C@H](CO)N(C)CC4)C(O)=CC(O)=C13 |
| Purity: | 99.77 |
| Description: | Voruciclib is an orally active and selective CDK inhibitor with Ki values of 0.626 nM-9.1 nM. Voruciclib potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL)[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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