ZK 216348 [CAS 669073-68-1]
Partner: MedChemexpress LLC
CAS No: | 669073-68-1 |
Applications: | Metabolism-sugar/lipid metabolism |
MW: | 476.45 |
Formula: | C24H23F3N2O5 |
SMILES: | O=C1C2=CC=C(C=C2C(C)=NO1)NC(C(C(F)(F)F)(O)CC(C)(C3=C4C(CCO4)=CC=C3)C)=O |
Purity: | 98.59 |
Description: | ZK 216348 ((+)-ZK 216348) is a nonsteroidal selective glucocorticoid receptor agonist with an IC50 of 20.3 nM. ZK 216348 also binds to Progesterone and mineralocorticoid receptors with IC50s of 20.4 nM and 79.9 nM, respectively. ZK 216348 has antiinflammatory activity similar to Prednisolone and induces less transactivation-mediated side effects[1][2]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
Insight Biotechnology Ltd reserves the right to change pricing without notice