ZT-12-037-01 [CAS 2328073-61-4] (10mM in DMSO)
Partner: MedChemexpress LLC
| CAS No: | 2328073-61-4 |
| Applications: | Cancer-Kinase/protease |
| MW: | 385.50 |
| Formula: | C21H31N5O2 |
| SMILES: | COC1=CC2=NC(NC3CC3)=NC(NC4CCN(C(C)C)CC4)=C2C=C1OC |
| Purity: | 98.67 |
| Description: | ZT-12-037-01 is a STK19-targeted inhibitor, has a high-affinity interaction with STK19 protein and inhibits oncogenic NRAS-driven melanocyte malignant transformation. ZT-12-037-01 is an ATP-competitive inhibitor, inhibiting phosphorylation of NRAS (major isoform of Ras family) with an IC50 of 24 nM[1]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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