PI-1840 [CAS 1401223-22-0]
Partner: MedChemexpress LLC
| CAS No: | 1401223-22-0 |
| Applications: | Cancer-Kinase/protease |
| MW: | 394.47 |
| Formula: | C22H26N4O3 |
| SMILES: | O=C(N(C(C)C)CC1=NC(C2=CC=CN=C2)=NO1)COC3=CC=C(CCC)C=C3 |
| Purity: | 98.78 |
| Description: | PI-1840 is a potent and selective chymotrypsin-like (CT-L) inhibitor for with an IC50 value of 27 nM. PI-1840 inhibits cell proliferation and arrest cell cycle at G2/M phase. PI-1840 induces apoptosis and induces autophagy. PI-1840 induces the accumulation of proteasome substrates p27, Bax, and IκB-α[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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