BRD6989 [CAS 642008-81-9]
Partner: MedChemexpress LLC
CAS No: | 642008-81-9 |
Applications: | COVID-19-anti-virus |
MW: | 264.33 |
Formula: | C16H16N4 |
SMILES: | N#CC1=C(C2=CC=CN=C2)C3=C(N=C1N)CCC(C)C3 |
Purity: | 99.56 |
Description: | BRD6989, an analog of the natural product cortistatin A (dCA), inhibits CDK8 and upregulates IL-10. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes[1]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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