GW274150 (phosphate) [CAS 438542-15-5]
Partner: MedChemexpress LLC
| CAS No: | 438542-15-5 |
| Applications: | Neuroscience-Neurodegeneration |
| MW: | 317.30 |
| Formula: | C8H20N3O6PS |
| SMILES: | CC(NCCSCC[C@H](N)C(O)=O)=N.O=P(O)(O)O |
| Purity: | 99.85 |
| Description: | GW274150 phosphate is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 ?M; Kd=40 nM) and rat iNOS (ED50=1.15 ?M). GW274150 phosphate displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 phosphate exerts a protective role in an acute model of lung injury inflammation[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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