Data Sheet

MSDS

CXCR2-IN-2 [CAS 1838123-21-9]

CAS No:	1838123-21-9
Applications:	COVID-19-immunoregulation
MW:	414.90
Formula:	C₁₈H₂₃ClN₂O₅S
SMILES:	O=C(N[C@H]1C(C)=CCC1)NC2=CC=C(Cl)C(S(=O)([C@]3(C)COCC3)=O)=C2O
Purity:	99.52
Description:	CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5.2 nM/1 nM in ?-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and >1900-fold selectivity over all other chemokine receptors. CXCR2-IN-2 inhibits human whole blood Gro-? induced CD11b expression with an IC50 of 0.04 ?M[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only