(Rac)-BRD0705 [CAS 1597440-03-3] (10mM in DMSO)
Partner: MedChemexpress LLC
| CAS No: | 1597440-03-3 |
| Applications: | Cancer-Kinase/protease |
| MW: | 321.42 |
| Formula: | C20H23N3O |
| SMILES: | O=C1C2=C(N=C3C(C2(CC)C4=CC=CC=C4)=CNN3)CC(C)(C)C1 |
| Purity: | 99.17 |
| Description: | (Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3? inhibitor with an IC50 of 66 nM and a Kd of 4.8 ?M. BRD0705 displays increased selectivity for GSK3? (8-fold) versus GSK3? (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML)[1][2]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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