Data Sheet

MSDS

(2S,3R)-LP99 [CAS 1808948-28-8]

CAS No:	1808948-28-8
Applications:	COVID-19-immunoregulation
MW:	516.05
Formula:	C₂₆H₃₀ClN₃O₄S
SMILES:	CC(CS(=O)(N[C@@H]([C@@H](N1C2=CC3=C(C(C)=CC(N3C)=O)C=C2)C4=CC=C(C=C4)Cl)CCC1=O)=O)C
Description:	(2S,3R)-LP99 is a potent and selective BRD7 and BRD9 inhibitor with an KD of 99 nM for BRD9. (2S,3R)-LP99 inhibits the association of BRD7 and BRD9 to acetylated histones in vitro and in cells. (2S,3R)-LP99 demonstrates that BRD7/9 plays a role in regulating pro-inflammatory cytokine secretion[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only