Description: | EB-3D is a potent and selective choline kinase ? (ChoK?) inhibitor, with an IC50 of 1 ?M for ChoK?1. EB-3D exerts effects on ChoK? expression, AMPK activation, apoptosis, endoplasmic reticulum stress and lipid metabolism. EB-3D exhibits a potent antiproliferative activity in a panel of T-leukemia cell lines. Anti-cancer activity[1][2][3]. |