Data Sheet

MSDS

Vorinostat-d5 [CAS 1132749-48-4]

CAS No:	1132749-48-4
MW:	269.35
Formula:	C₁₄H₁₅D₅N₂O₃
SMILES:	O=C(NO)CCCCCCC(NC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O
Purity:	99.0
Description:	Vorinostat-d5 (SAHA-d5) is the deuterium labeled Vorinostat. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis[1][4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification[7].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only