Description: | (E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) is a potent and selective GSK-3?/? inhibitor, with an IC50 of 10 nM. (E/Z)-BIO-acetoxime shows more than 200-flod selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B (IC50=2.4, 4.3, 63 ?M)[1]. |