Description: | Gamma-glutamylcysteine (?-Glutamylcysteine) TFA, an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine TFA also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-?, IL-6, and IL-1?). Gamma-glutamylcysteine TFA attenuates the changes in metalloproteinase activity in oligomeric A?40-treated astrocytes[1]. |