Data Sheet

MSDS

CDDO-dhTFEA [CAS 1191265-33-4]

CAS No:	1191265-33-4
Applications:	Neuroscience-Neuromodulation
MW:	574.72
Formula:	C₃₃H₄₅F₃N₂O₃
SMILES:	CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CCC(C)(C[C@]2([C@]13[H])[H])C)C(NCC(F)(F)F)=O)C)4C)5[H])C(C(C#N)=C[C@]5(C)[C@@]4([H])CC3=O)=O
Purity:	99.71
Description:	CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-?B[1]. CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-?B and transforming growth factor-? pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats[2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only