C188 [CAS 823828-18-8]
Partner: MedChemexpress LLC
| CAS No: | 823828-18-8 |
| Applications: | Cancer-Kinase/protease |
| MW: | 433.45 |
| Formula: | C19H15NO7S2 |
| SMILES: | O=C(O)C1=CC=C(S(=O)(NC2=C3C=CC=CC3=C(O)C(SCC(O)=O)=C2)=O)C=C1 |
| Purity: | 97.0 |
| Description: | C188 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro (EC50= 0.7 ?M). |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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