C188-9 [CAS 432001-19-9]
Partner: MedChemexpress LLC
| CAS No: | 432001-19-9 |
| Applications: | Cancer-Kinase/protease |
| MW: | 471.52 |
| Formula: | C27H21NO5S |
| SMILES: | O=S(C1=CC=C(OC)C=C1)(NC2=C3C=CC=CC3=C(O)C(C4=C5C=CC=CC5=CC=C4O)=C2)=O |
| Purity: | 99.90 |
| Description: | C188-9 (TTI-101) is a STAT3 inhibitor, with a Kd of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts[1][2][3][4]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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