3'-Azido-3'-deoxy-5-methylcytidine [CAS 1282040-14-5] (10mM in DMSO)
Partner: MedChemexpress LLC
CAS No: | 1282040-14-5 |
Applications: | Neuroscience-Neuromodulation |
MW: | 282.26 |
Formula: | C10H14N6O4 |
SMILES: | O[C@@H]1[C@H](N=[N+]=[N-])[C@@H](CO)O[C@H]1N2C=C(C)C(N)=NC2=O |
Purity: | 99.15 |
Description: | 3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 ?M in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 ?M in peripheral blood mononuclear (PBM) cells[1]. 3'-Azido-3'-deoxy-5-methylcytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. |
Shipping Conditions: | Ship on cold packs |
Usage: | Research Use Only |
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