Data Sheet

MSDS

FT113 [CAS 1630808-89-7]

CAS No:	1630808-89-7
Applications:	Cancer-programmed cell death
MW:	409.41
Formula:	C₂₂H₂₀FN₃O₄
SMILES:	O=C(C1(CC1)O)N2CCN(C(C3=CC=C(C4=NC5=C(C=C(F)C=C5)O4)C=C3)=O)CC2
Purity:	99.61
Description:	FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC50, 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only